AstraZeneca: Expert discusses EMA's stance on COVID vaccine
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More than 33.9 million people have now had a first dose of the vaccine in the UK, with a quarter now fully vaccinated. Data from the ZOE Covid Symptom Tracking Study, a surveillance tool that tracks Britain’s outbreak, showed skin burning, rashes, and red welts on the lips and face are possible side effects from the vaccine that people need to be aware of.
The app also found that headaches, fatigue and fever were more common with the AstraZeneca vaccine.
King’s College London scientists also found headaches were the most common side effect.
Other symptoms recorded from the AstraZeneca vaccine according to the MHRA include one in 10 people will suffer a headache, chills, fever symptoms and nausea.
People who had been infected with Covid before were three times as likely to have full-body side effects from the first dose of the Pfizer vaccine as those who had not suffered with a known infection before.
They were also twice as likely to experience the effects as those having a first dose of AstraZeneca’s jab.
In fact sheets describing each vaccine, manufacturers listed additional possible side effects—including diarrhoea, joint pain, swollen lymph nodes, hives, rashes and facial swelling—and noted that there could be even more side effects beyond those specified.
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In a study published in the Lancet, vaccine side-effects after vaccination in users of the COVID Symptom Study app was investigated.
The study noted: “In this prospective observational study, we examined the proportion and probability of self-reported systemic and local side-effects within eight days of vaccination in individuals using the COVID Symptom Study app who received one or two doses of the Pfizer vaccine or one dose of the AstraZeneca vaccine.
“Systemic side-effects were reported by 13.5 percent of individuals after the first dose of the Pfizer vaccine, by 22 percent after the second dose and by 33.7 percent after the first dose the AstraZeneca vaccine.
“Local side-effects were reported by 71.9 percent of individuals after the first dose of the Pfizer vaccine, by 68.5 percent after the second dose of Pfizer vaccine, and by 58.7 percent after the first dose of the AstraZeneca vaccine.
“Systemic side-effects were more common (1·6 times after the first dose of the AstraZeneca vaccine and 2.9 times after the first dose of the Pfizer vaccine).”
The study found that headaches and fatigue were more common in women than in men, in people aged 55 years or younger than in people older than 55 years, and after the second dose compared to the first dose.
Among vaccinated app users, 25.4 percent indicated having one or more systemic adverse effect, and 66.2 percent reported one or more local adverse effect.
The most commonly reported systemic side-effects were fatigue and headache overall.
Tenderness and local pain around the injection site were the most frequently reported local effects, occurring most often on the day after injection and lasting a mean of 1.2 days.
Other side-effects reported in the app included allergic skin reactions such as skin burning, rashes, and red welts on the lips and face, were reported by 1.7 percent of users across both types of vaccine.
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